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Interleukin 12: still a promising candidate for tumor immunotherapy?

Interleukin 12 (IL-12) seemed to represent the ideal candidate for tumor immunotherapy, due to its ability to activate both innate (NK cells) and adaptive (cytotoxic T lymphocytes) immunities. However, despite encouraging results in animal models, very modest antitumor effects of IL-12 in early clin...

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Detalles Bibliográficos
Autores principales: Lasek, Witold, Zagożdżon, Radosław, Jakobisiak, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994286/
https://www.ncbi.nlm.nih.gov/pubmed/24514955
http://dx.doi.org/10.1007/s00262-014-1523-1