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Low-solubility particles and a Trojan-horse type mechanism of toxicity: the case of cobalt oxide on human lung cells

BACKGROUND: The mechanisms of toxicity of metal oxide particles towards lung cells are far from being understood. In particular, the relative contribution of intracellular particulate versus solubilized fractions is rarely considered as it is very challenging to assess, especially for low-solubility...

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Detalles Bibliográficos
Autores principales: Ortega, Richard, Bresson, Carole, Darolles, Carine, Gautier, Céline, Roudeau, Stéphane, Perrin, Laura, Janin, Myriam, Floriani, Magali, Aloin, Valérie, Carmona, Asuncion, Malard, Véronique
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994290/
https://www.ncbi.nlm.nih.gov/pubmed/24669904
http://dx.doi.org/10.1186/1743-8977-11-14