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Alteration of Striatal Tetrahydrobiopterin in Iron-Induced Unilateral Model of Parkinson's Disease

It has been suggested that transition metal ions such as iron can produce an oxidative injuries to nigrostriatal dopaminergic neurons, like Parkinson's disease (PD) and subsequent compensative increase of tetrahydrobiopterin (BH(4)) during the disease progression induces the aggravation of dopa...

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Detalles Bibliográficos
Autores principales: Aryal, Bijay, Lee, Jin-Koo, Kim, Hak Rim, Kim, Hyung-Gun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994299/
https://www.ncbi.nlm.nih.gov/pubmed/24757374
http://dx.doi.org/10.4196/kjpp.2014.18.2.129