Regulatory B Subunits of Protein Phosphatase 2A Are Involved in Site-specific Regulation of Tau Protein Phosphorylation

Overexpression of amyloid precursor protein with the Swedish mutation causes abnormal hyperphosphorylation of the microtubule-associated protein tau. Hyperphosphorylated isoforms of tau are major components of neurofibrillary tangles, which are histopathological hallmarks of Alzheimer's disease...

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Detalles Bibliográficos
Autores principales: Yu, Un Young, Yoo, Byong Chul, Ahn, Jung-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Physiological Society and The Korean Society of Pharmacology 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994303/
https://www.ncbi.nlm.nih.gov/pubmed/24757378
http://dx.doi.org/10.4196/kjpp.2014.18.2.155

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994303/
https://www.ncbi.nlm.nih.gov/pubmed/24757378
http://dx.doi.org/10.4196/kjpp.2014.18.2.155

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