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Microglia and motor neurons during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthase
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting the motor system. Although the etiology of the disease is not fully understood, microglial activation and neuroinflammation are thought to play a role in disease progression. METHODS: We examined the immun...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994340/ https://www.ncbi.nlm.nih.gov/pubmed/24655927 http://dx.doi.org/10.1186/1742-2094-11-55 |