Microglia and motor neurons during disease progression in the SOD1(G93A) mouse model of amyotrophic lateral sclerosis: changes in arginase1 and inducible nitric oxide synthase

BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease affecting the motor system. Although the etiology of the disease is not fully understood, microglial activation and neuroinflammation are thought to play a role in disease progression. METHODS: We examined the immun...

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Detalles Bibliográficos
Autores principales: Lewis, Katherine E, Rasmussen, Anna L, Bennett, William, King, Anna, West, Adrian K, Chung, Roger S, Chuah, Meng Inn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994340/
https://www.ncbi.nlm.nih.gov/pubmed/24655927
http://dx.doi.org/10.1186/1742-2094-11-55

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