Astrocytic expression of HIV-1 viral protein R in the hippocampus causes chromatolysis, synaptic loss and memory impairment

BACKGROUND: HIV-infected individuals are at an increased risk of developing neurological abnormalities. HIV induces neurotoxicity by host cellular factors and individual viral proteins. Some of these proteins including viral protein R (Vpr) promote immune activation and neuronal damage. Vpr is known...

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Detalles Bibliográficos
Autores principales: Torres, Lilith, Noel, Richard J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994341/
https://www.ncbi.nlm.nih.gov/pubmed/24655810
http://dx.doi.org/10.1186/1742-2094-11-53

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994341/
https://www.ncbi.nlm.nih.gov/pubmed/24655810
http://dx.doi.org/10.1186/1742-2094-11-53

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