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Astrocytic expression of HIV-1 viral protein R in the hippocampus causes chromatolysis, synaptic loss and memory impairment

BACKGROUND: HIV-infected individuals are at an increased risk of developing neurological abnormalities. HIV induces neurotoxicity by host cellular factors and individual viral proteins. Some of these proteins including viral protein R (Vpr) promote immune activation and neuronal damage. Vpr is known...

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Detalles Bibliográficos
Autores principales:	Torres, Lilith, Noel, Richard J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994341/ https://www.ncbi.nlm.nih.gov/pubmed/24655810 http://dx.doi.org/10.1186/1742-2094-11-53

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