Mutated tumor alleles are expressed according to their DNA frequency

The transcription of tumor mutations from DNA into RNA has implications for biology, epigenetics and clinical practice. It is not clear if mutations are in general transcribed and, if so, at what proportion to the wild-type allele. Here, we examined the correlation between DNA mutation allele freque...

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Detalles Bibliográficos
Autores principales: Castle, John C., Loewer, Martin, Boegel, Sebastian, Tadmor, Arbel D., Boisguerin, Valesca, de Graaf, Jos, Paret, Claudia, Diken, Mustafa, Kreiter, Sebastian, Türeci, Özlem, Sahin, Ugur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994436/
https://www.ncbi.nlm.nih.gov/pubmed/24752137
http://dx.doi.org/10.1038/srep04743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994436/
https://www.ncbi.nlm.nih.gov/pubmed/24752137
http://dx.doi.org/10.1038/srep04743

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