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Mutated tumor alleles are expressed according to their DNA frequency
The transcription of tumor mutations from DNA into RNA has implications for biology, epigenetics and clinical practice. It is not clear if mutations are in general transcribed and, if so, at what proportion to the wild-type allele. Here, we examined the correlation between DNA mutation allele freque...
Autores principales: | Castle, John C., Loewer, Martin, Boegel, Sebastian, Tadmor, Arbel D., Boisguerin, Valesca, de Graaf, Jos, Paret, Claudia, Diken, Mustafa, Kreiter, Sebastian, Türeci, Özlem, Sahin, Ugur |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994436/ https://www.ncbi.nlm.nih.gov/pubmed/24752137 http://dx.doi.org/10.1038/srep04743 |
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