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Oridonin induces apoptosis and cell cycle arrest of gallbladder cancer cells via the mitochondrial pathway

BACKGROUND: Gallbladder cancer is the most frequent malignancy of the bile duct with high aggressive and extremely poor prognosis. The main objective of the paper was to investigate the inhibitory effects of oridonin, a diterpenoid isolated from Rabdosia rubescens, on gallbladder cancer both in vitr...

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Detalles Bibliográficos
Autores principales: Bao, Runfa, Shu, Yijun, Wu, Xiangsong, Weng, Hao, Ding, Qian, Cao, Yang, Li, Maolan, Mu, Jiasheng, Wu, Wenguang, Ding, Qichen, Tan, Zhujun, Liu, Tianyu, Jiang, Lin, Hu, Yunping, Gu, Jianfeng, Liu, Yingbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994450/
https://www.ncbi.nlm.nih.gov/pubmed/24655726
http://dx.doi.org/10.1186/1471-2407-14-217