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Gastrodia elata Blume alleviates L-DOPA-induced dyskinesia by normalizing FosB and ERK activation in a 6-OHDA-lesioned Parkinson’s disease mouse model

BACKGROUND: Gastrodia elata Blume (GEB), commonly used medicinal herb, has been reported as a promising candidate for neurodegenerative diseases such as Parkinson’s disease. The dopamine precursor, L-3,4-dihydroxyphenylalanine (L-DOPA), is the gold-standard drug for Parkinson’s disease, but long-ter...

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Detalles Bibliográficos
Autores principales: Doo, Ah-Reum, Kim, Seung-Nam, Hahm, Dae-Hyun, Yoo, Hye Hyun, Park, Ji-Yeun, Lee, Hyejung, Jeon, Songhee, Kim, Jongpil, Park, Seong-Uk, Park, Hi-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994477/
https://www.ncbi.nlm.nih.gov/pubmed/24650244
http://dx.doi.org/10.1186/1472-6882-14-107