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Gastrodia elata Blume alleviates L-DOPA-induced dyskinesia by normalizing FosB and ERK activation in a 6-OHDA-lesioned Parkinson’s disease mouse model
BACKGROUND: Gastrodia elata Blume (GEB), commonly used medicinal herb, has been reported as a promising candidate for neurodegenerative diseases such as Parkinson’s disease. The dopamine precursor, L-3,4-dihydroxyphenylalanine (L-DOPA), is the gold-standard drug for Parkinson’s disease, but long-ter...
Autores principales: | Doo, Ah-Reum, Kim, Seung-Nam, Hahm, Dae-Hyun, Yoo, Hye Hyun, Park, Ji-Yeun, Lee, Hyejung, Jeon, Songhee, Kim, Jongpil, Park, Seong-Uk, Park, Hi-Joon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994477/ https://www.ncbi.nlm.nih.gov/pubmed/24650244 http://dx.doi.org/10.1186/1472-6882-14-107 |
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