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The eIF2α kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression
The proper regulation of translation is required for the expression of long-lasting synaptic plasticity. A major site of translational control involves the phosphorylation of eukaryotic initiation factor 2 α (eIF2α) by PKR-like endoplasmic reticulum (ER) kinase (PERK). To determine the role of PERK...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994503/ https://www.ncbi.nlm.nih.gov/pubmed/24741110 http://dx.doi.org/10.1101/lm.032219.113 |