The eIF2α kinase PERK limits the expression of hippocampal metabotropic glutamate receptor-dependent long-term depression

The proper regulation of translation is required for the expression of long-lasting synaptic plasticity. A major site of translational control involves the phosphorylation of eukaryotic initiation factor 2 α (eIF2α) by PKR-like endoplasmic reticulum (ER) kinase (PERK). To determine the role of PERK...

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Detalles Bibliográficos
Autores principales: Trinh, Mimi A., Ma, Tao, Kaphzan, Hanoch, Bhattacharya, Aditi, Antion, Marcia D., Cavener, Douglas R., Hoeffer, Charles A., Klann, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994503/
https://www.ncbi.nlm.nih.gov/pubmed/24741110
http://dx.doi.org/10.1101/lm.032219.113

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