Triosephosphate Isomerase Is Dispensable In Vitro yet Essential for Mycobacterium tuberculosis To Establish Infection

Triosephosphate isomerase (TPI) catalyzes the interconversion of dihydroxyacetone phosphate (DHAP) and glyceraldehyde-3-phosphate (G3P). This reaction is required for glycolysis and gluconeogenesis, and tpi has been predicted to be essential for growth of Mycobacterium tuberculosis. However, when st...

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Detalles Bibliográficos
Autores principales: Trujillo, Carolina, Blumenthal, Antje, Marrero, Joeli, Rhee, Kyu Y., Schnappinger, Dirk, Ehrt, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Microbiology 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994511/
https://www.ncbi.nlm.nih.gov/pubmed/24757211
http://dx.doi.org/10.1128/mBio.00085-14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994511/
https://www.ncbi.nlm.nih.gov/pubmed/24757211
http://dx.doi.org/10.1128/mBio.00085-14

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