Distribution of genetic polymorphisms of genes encoding drug metabolizing enzymes & drug transporters - a review with Indian perspective

Phase I and II drug metabolizing enzymes (DME) and drug transporters are involved in the absorption, distribution, metabolism as well as elimination of many therapeutic agents, toxins and various pollutants. Presence of genetic polymorphisms in genes encoding these proteins has been associated with...

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Detalles Bibliográficos
Autores principales: Umamaheswaran, Gurusamy, Kumar, Dhakchinamoorthi Krishna, Adithan, Chandrasekaran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994740/
https://www.ncbi.nlm.nih.gov/pubmed/24604039