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Targeting PI3K/Akt/mTOR Signaling in Cancer

The phosphatidylinositol-3-kinase (PI3K)/Akt and the mammalian target of rapamycin (mTOR) signaling pathways are two pathways crucial to many aspects of cell growth and survival, in physiological as well as in pathological conditions (e.g., cancer). Indeed, they are so interconnected that, in a cert...

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Detalles Bibliográficos
Autores principales: Porta, Camillo, Paglino, Chiara, Mosca, Alessandra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995050/
https://www.ncbi.nlm.nih.gov/pubmed/24782981
http://dx.doi.org/10.3389/fonc.2014.00064