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Kir3 channel ontogeny – the role of Gβγ subunits in channel assembly and trafficking

The role of Gβγ subunits in Kir3 channel gating is well characterized. Here, we have studied the role of Gβγ dimers during their initial contact with Kir3 channels, prior to their insertion into the plasma membrane. We show that distinct Gβγ subunits play an important role in orchestrating and fine-...

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Detalles Bibliográficos
Autores principales: Zylbergold, Peter, Sleno, Rory, Khan, Shahriar M., Jacobi, Ashley M., Belhke, Mark A., Hébert, Terence E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995069/
https://www.ncbi.nlm.nih.gov/pubmed/24782712
http://dx.doi.org/10.3389/fncel.2014.00108