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Rab3Gap1 mediates exocytosis of Claudin-1 and tight junction formation during epidermal barrier acquisition

Epidermal barrier acquisition during late murine gestation is accompanied by an increase in Akt kinase activity and cJun dephosphorlyation. The latter is directed by the Ppp2r2a regulatory subunit of the Pp2a phosphatase. This was accompanied by a change of Claudin-1 localisation to the cell surface...

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Detalles Bibliográficos
Autores principales: Youssef, G., Gerner, L., Naeem, A.S., Ralph, O., Ono, M., O’Neill, C.A., O’Shaughnessy, R.F.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995087/
https://www.ncbi.nlm.nih.gov/pubmed/23685254
http://dx.doi.org/10.1016/j.ydbio.2013.04.034