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Cardiac hypertrophy associated with myeloproliferative neoplasms in JAK2V617F transgenic mice

BACKGROUND: Myeloproliferative neoplasms (MPNs) are blood malignancies manifested in increased production of red blood cells, white blood cells, and/or platelets. A major molecular lesion associated with the diseases is JAK2V617F, an activation mutation form of tyrosine kinase JAK2. Cardiovascular e...

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Detalles Bibliográficos
Autores principales: Shi, Kaiyao, Zhao, Wanke, Chen, Yun, Ho, Wanting Tina, Yang, Ping, Zhao, Zhizhuang Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995113/
https://www.ncbi.nlm.nih.gov/pubmed/24646493
http://dx.doi.org/10.1186/1756-8722-7-25