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Cardiac hypertrophy associated with myeloproliferative neoplasms in JAK2V617F transgenic mice
BACKGROUND: Myeloproliferative neoplasms (MPNs) are blood malignancies manifested in increased production of red blood cells, white blood cells, and/or platelets. A major molecular lesion associated with the diseases is JAK2V617F, an activation mutation form of tyrosine kinase JAK2. Cardiovascular e...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995113/ https://www.ncbi.nlm.nih.gov/pubmed/24646493 http://dx.doi.org/10.1186/1756-8722-7-25 |