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Sonic Hedgehog Pathway Contributes to Gastric Cancer Cell Growth and Proliferation

The Sonic Hedgehog (Shh) signaling pathway is commonly activated in gastrointestinal cancer. However, our understanding of the Shh pathway in gastric cancer remains limited. Here we examined the effects of cyclopamine, a specific inhibitor of the Shh signaling pathway, on cell growth and proliferati...

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Detalles Bibliográficos
Autores principales: Wan, Jianhua, Zhou, Ji, Zhao, Hailong, Wang, Mei, Wei, Zhuanqin, Gao, Hongyan, Wang, Yongzhong, Cui, Hongjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995118/
https://www.ncbi.nlm.nih.gov/pubmed/24804165
http://dx.doi.org/10.1089/biores.2014.0001