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Cofactor Specificity Engineering of Streptococcus mutans NADH Oxidase 2 for NAD(P)(+) Regeneration in Biocatalytic Oxidations

Soluble water-forming NAD(P)H oxidases constitute a promising NAD(P)(+) regeneration method as they only need oxygen as cosubstrate and produce water as sole byproduct. Moreover, the thermodynamic equilibrium of O(2) reduction is a valuable driving force for mostly energetically unfavorable biocatal...

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Detalles Bibliográficos
Autores principales: Petschacher, Barbara, Staunig, Nicole, Müller, Monika, Schürmann, Martin, Mink, Daniel, De Wildeman, Stefaan, Gruber, Karl, Glieder, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995211/
https://www.ncbi.nlm.nih.gov/pubmed/24757503
http://dx.doi.org/10.5936/csbj.201402005