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Site-specific functionalization of proteins and their applications to therapeutic antibodies

Protein modifications are often required to study structure and function relationships. Instead of the random labeling of lysine residues, methods have been developed to (sequence) specific label proteins. Next to chemical modifications, tools to integrate new chemical groups for bioorthogonal react...

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Detalles Bibliográficos
Autores principales: van Vught, Remko, Pieters, Roland J, Breukink, Eefjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology (RNCSB) Organization 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995230/
https://www.ncbi.nlm.nih.gov/pubmed/24757499
http://dx.doi.org/10.5936/csbj.201402001