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Site-specific functionalization of proteins and their applications to therapeutic antibodies
Protein modifications are often required to study structure and function relationships. Instead of the random labeling of lysine residues, methods have been developed to (sequence) specific label proteins. Next to chemical modifications, tools to integrate new chemical groups for bioorthogonal react...
Autores principales: | van Vught, Remko, Pieters, Roland J, Breukink, Eefjan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology (RNCSB) Organization
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995230/ https://www.ncbi.nlm.nih.gov/pubmed/24757499 http://dx.doi.org/10.5936/csbj.201402001 |
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