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Site-specific Labeling of a Protein Lysine Residue By Novel Kinetic Labeling Combinatorial Libraries
The first example of a kinetic labeling library designed to enable the discovery of affinity labels is presented. Each library component (1) consists of a variable peptidyl component linked to a biotinyl moiety by a 4-mercaptobenzoyl linker in thioester format. We demonstrate that an affinity label...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Research Network of Computational and Structural Biotechnology (RNCSB) Organization
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995232/ https://www.ncbi.nlm.nih.gov/pubmed/24757504 http://dx.doi.org/10.5936/csbj.201403001 |