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Expression of EpCAM(MF) and EpCAM(MT) variants in human carcinomas

AIMS: Regulated intramembrane proteolysis has been shown to be an important mechanism for oncogenic activation of epithelial cell adhesion molecule (EpCAM) through nuclear translocation of the intracellular domain EpICD. Recent studies have identified new membrane-bound EpCAM variants. To evaluate t...

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Detalles Bibliográficos
Autores principales: Fong, Dominic, Seeber, Andreas, Terracciano, Luigi, Kasal, Armin, Mazzoleni, Guido, Lehne, Florian, Gastl, Guenther, Spizzo, Gilbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995261/
https://www.ncbi.nlm.nih.gov/pubmed/24465008
http://dx.doi.org/10.1136/jclinpath-2013-201932