A disrupted RNA editing balance mediated by ADARs (Adenosine DeAminases that act on RNA) in human hepatocellular carcinoma

OBJECTIVE: Hepatocellular carcinoma (HCC) is a heterogeneous tumour displaying a complex variety of genetic and epigenetic changes. In human cancers, aberrant post-transcriptional modifications, such as alternative splicing and RNA editing, may lead to tumour specific transcriptome diversity. DESIGN...

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Detalles Bibliográficos
Autores principales: Chan, Tim Hon Man, Lin, Chi Ho, Qi, Lihua, Fei, Jing, Li, Yan, Yong, Kol Jia, Liu, Ming, Song, Yangyang, Chow, Raymond Kwok Kei, Ng, Vanessa Hui En, Yuan, Yun-Fei, Tenen, Daniel G, Guan, Xin-Yuan, Chen, Leilei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Hepatology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995272/
https://www.ncbi.nlm.nih.gov/pubmed/23766440
http://dx.doi.org/10.1136/gutjnl-2012-304037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995272/
https://www.ncbi.nlm.nih.gov/pubmed/23766440
http://dx.doi.org/10.1136/gutjnl-2012-304037

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