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Characterisation of faecal protease activity in irritable bowel syndrome with diarrhoea: origin and effect of gut transit

OBJECTIVES: Faecal serine proteases (FSPs) may play a role in irritable bowel syndrome with diarrhoea (IBS-D), but their origin is unclear. We aimed to structurally characterise them and define the impact of colonic cleansing and transit time. DESIGN: Faecal samples were obtained from 30 healthy vol...

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Detalles Bibliográficos
Autores principales: Tooth, David, Garsed, Klara, Singh, Gulzar, Marciani, Luca, Lam, Ching, Fordham, Imogen, Fields, Annie, Banwait, Rawinder, Lingaya, Melanie, Layfield, Robert, Hastings, Maggie, Whorwell, Peter, Spiller, Robin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995279/
https://www.ncbi.nlm.nih.gov/pubmed/23911555
http://dx.doi.org/10.1136/gutjnl-2012-304042