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Ciclosporin 10 years on: indications and efficacy

Ciclosporin is a lipophilic cyclic polypeptide with powerful immunosuppressive and immunomodulatory properties that has been used in veterinary medicine for two decades. It is a calcineurin inhibitor whose principal mode of action is to inhibit T cell activation. The drug is principally absorbed fro...

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Detalles Bibliográficos
Autores principales: Forsythe, Peter, Paterson, Sue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995292/
https://www.ncbi.nlm.nih.gov/pubmed/24682697
http://dx.doi.org/10.1136/vr.102484