Optimization of heterologous protein production in Chinese hamster ovary cells under overexpression of spliced form of human X-box binding protein

BACKGROUND: The optimization of protein production is a complex and challenging problem in biotechnology. Different techniques for transcription, translation engineering and the optimization of cell culture conditions have been used to improve protein secretion, but there remain many open problems i...

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Detalles Bibliográficos
Autores principales: Gulis, Galina, Simi, Kelly Cristina Rodrigues, de Toledo, Renata Rodrigues, Maranhao, Andrea Queiroz, Brigido, Marcelo Macedo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995513/
https://www.ncbi.nlm.nih.gov/pubmed/24725707
http://dx.doi.org/10.1186/1472-6750-14-26

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995513/
https://www.ncbi.nlm.nih.gov/pubmed/24725707
http://dx.doi.org/10.1186/1472-6750-14-26

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