Genes with a large intronic burden show greater evolutionary conservation on the protein level

BACKGROUND: The existence of introns in eukaryotic genes is believed to provide an evolutionary advantage by increasing protein diversity through exon shuffling and alternative splicing. However, this eukaryotic feature is associated with the necessity of exclusion of intronic sequences, which requi...

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Detalles Bibliográficos
Autores principales: Gorlova, Olga, Fedorov, Alexey, Logothetis, Christopher, Amos, Christopher, Gorlov, Ivan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995522/
https://www.ncbi.nlm.nih.gov/pubmed/24629165
http://dx.doi.org/10.1186/1471-2148-14-50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995522/
https://www.ncbi.nlm.nih.gov/pubmed/24629165
http://dx.doi.org/10.1186/1471-2148-14-50

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