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Genes with a large intronic burden show greater evolutionary conservation on the protein level
BACKGROUND: The existence of introns in eukaryotic genes is believed to provide an evolutionary advantage by increasing protein diversity through exon shuffling and alternative splicing. However, this eukaryotic feature is associated with the necessity of exclusion of intronic sequences, which requi...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995522/ https://www.ncbi.nlm.nih.gov/pubmed/24629165 http://dx.doi.org/10.1186/1471-2148-14-50 |