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Dose selection method for pharmacokinetic study in hemodialysis patients using a subpharmacological dose: oseltamivir as a model drug

BACKGROUND: Dose selection is an important step in pharmacokinetic (PK) studies of hemodialysis patients. We propose a simulation-based dose-selection method for PK studies of hemodialysis patients using a subpharmacological dose of oseltamivir as a model drug. METHODS: The concentrations of oseltam...

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Detalles Bibliográficos
Autores principales: Kim, Dong Ki, Lee, Jay Wook, Shin, Kwang-Hee, Kim, Sejoong, Oh, Kook-Hwan, Kim, Myounghee, Yu, Kyung-Sang, Lee, Jung Pyo, Lim, Chun-Soo, Kim, Yon Su, Joo, Kwon Wook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995549/
https://www.ncbi.nlm.nih.gov/pubmed/24636040
http://dx.doi.org/10.1186/1471-2369-15-46