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Regulatory mechanisms of betacellulin in CXCL8 production from lung cancer cells

BACKGROUND: Betacellulin (BTC), a member of the epidermal growth factor (EGF) family, binds and activates ErbB1 and ErbB4 homodimers. BTC was expressed in tumors and involved in tumor growth progression. CXCL8 (interleukin-8) was involved in tumor cell proliferation via the transactivation of the ep...

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Detalles Bibliográficos
Autores principales: Shi, Lin, Wang, Lingyan, Wang, Beibei, Cretoiu, Sanda Maria, Wang, Qun, Wang, Xiangdong, Chen, Chengshui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995556/
https://www.ncbi.nlm.nih.gov/pubmed/24629040
http://dx.doi.org/10.1186/1479-5876-12-70