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Regulation gene expression of miR200c and ZEB1 positively enhances effect of tumor vaccine B16F10/GPI-IL-21 on inhibition of melanoma growth and metastasis
BACKGROUND: Genetically modified cells have been shown to be one of the most effective tumor vaccine strategies. However, in many cases, such as in melanoma, induction of a potent immune responses against the disease still remains a major challenge. Thus, novel strategies to reinforce tumor vaccine...
Hlavní autoři: | , , , , , , , , |
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Médium: | Online Článek Text |
Jazyk: | English |
Vydáno: |
BioMed Central
2014
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Témata: | |
On-line přístup: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995592/ https://www.ncbi.nlm.nih.gov/pubmed/24625224 http://dx.doi.org/10.1186/1479-5876-12-68 |