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Regulation gene expression of miR200c and ZEB1 positively enhances effect of tumor vaccine B16F10/GPI-IL-21 on inhibition of melanoma growth and metastasis

BACKGROUND: Genetically modified cells have been shown to be one of the most effective tumor vaccine strategies. However, in many cases, such as in melanoma, induction of a potent immune responses against the disease still remains a major challenge. Thus, novel strategies to reinforce tumor vaccine...

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Podrobná bibliografie
Hlavní autoři: Wang, Xiaoying, He, Xiangfeng, Zhao, Fengshu, Wang, Jing, Zhang, Hongyi, Shi, Fangfang, Zhang, Yunxia, Cai, Kai, Dou, Jun
Médium: Online Článek Text
Jazyk:English
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995592/
https://www.ncbi.nlm.nih.gov/pubmed/24625224
http://dx.doi.org/10.1186/1479-5876-12-68