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Cell-autonomous heparanase modulates self-renewal and migration in bone marrow-derived mesenchymal stem cells

BACKGROUND: Stem cell-fate is highly regulated by stem cell niche, which is composed of a distinct microenvironment, including neighboring cells, signals and extracellular matrix. Bone marrow-derived mesenchymal stem cells (BM-MSCs) are multipotent stem cells and are potentially applicable in wide v...

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Detalles Bibliográficos
Autores principales: Cheng, Chun-Chun, Lee, Yen-Hua, Lin, Shau-Ping, HuangFu, Wei-Chun, Liu, I-Hsuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995613/
https://www.ncbi.nlm.nih.gov/pubmed/24624965
http://dx.doi.org/10.1186/1423-0127-21-21