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Correlation of biomarkers for parasite burden and immune activation with acute kidney injury in severe falciparum malaria

BACKGROUND: Acute kidney injury (AKI) complicating severe Plasmodium falciparum malaria occurs in up to 40% of adult patients. The case fatality rate reaches 75% in the absence of renal replacement therapy (RRT). The precise pathophysiology of AKI in falciparum malaria remains unclear. Histopatholog...

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Detalles Bibliográficos
Autores principales: Plewes, Katherine, Royakkers, Annick A, Hanson, Josh, Hasan, Md Mahtab Uddin, Alam, Shamsul, Ghose, Aniruddha, Maude, Richard J, Stassen, Pauline M, Charunwatthana, Prakaykaew, Lee, Sue J, Turner, Gareth DH, Dondorp, Arjen M, Schultz, Marcus J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995633/
https://www.ncbi.nlm.nih.gov/pubmed/24618154
http://dx.doi.org/10.1186/1475-2875-13-91