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DPP-4 Inhibitor Attenuates Toxic Effects of Indoxyl Sulfate on Kidney Tubular Cells

Diabetic nephropathy is a common causative factor of chronic kidney disease (CKD). DPP-4 inhibitor has the ability to improve kidney function and renal microvasculature. In the present study, we investigate the deleterious effects of IS on proximal tubular cells and the protective role of DPP-4 inhi...

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Detalles Bibliográficos
Autores principales: Wang, Wei-Jie, Chang, Chen-Hung, Sun, Mao-Feng, Hsu, Sheng-Feng, Weng, Ching-Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995638/
https://www.ncbi.nlm.nih.gov/pubmed/24755682
http://dx.doi.org/10.1371/journal.pone.0093447