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Modulation of STAT3 Folding and Function by TRiC/CCT Chaperonin

Signal transducer and activator of transcription 3 (Stat3) transduces signals of many peptide hormones from the cell surface to the nucleus and functions as an oncoprotein in many types of cancers, yet little is known about how it achieves its native folded state within the cell. Here we show that S...

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Detalles Bibliográficos
Autores principales: Kasembeli, Moses, Lau, Wilson Chun Yu, Roh, Soung-Hun, Eckols, T. Kris, Frydman, Judith, Chiu, Wah, Tweardy, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995649/
https://www.ncbi.nlm.nih.gov/pubmed/24756126
http://dx.doi.org/10.1371/journal.pbio.1001844