Mutations in BIN1 Associated with Centronuclear Myopathy Disrupt Membrane Remodeling by Affecting Protein Density and Oligomerization

The regulation of membrane shapes is central to many cellular phenomena. Bin/Amphiphysin/Rvs (BAR) domain-containing proteins are key players for membrane remodeling during endocytosis, cell migration, and endosomal sorting. BIN1, which contains an N-BAR domain, is assumed to be essential for biogen...

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Detalles Bibliográficos
Autores principales: Wu, Tingting, Shi, Zheng, Baumgart, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995651/
https://www.ncbi.nlm.nih.gov/pubmed/24755653
http://dx.doi.org/10.1371/journal.pone.0093060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995651/
https://www.ncbi.nlm.nih.gov/pubmed/24755653
http://dx.doi.org/10.1371/journal.pone.0093060

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