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Targeted NGF siRNA Delivery Attenuates Sympathetic Nerve Sprouting and Deteriorates Cardiac Dysfunction in Rats with Myocardial Infarction

Nerve growth factor (NGF) is involved in nerve sprouting, hyper-innervation, angiogenesis, anti-apoptosis, and preservation of cardiac function after myocardial infarction (MI). Positively modulating NGF expression may represent a novel pharmacological strategy to improve post-infarction prognosis....

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Detalles Bibliográficos
Autores principales: Hu, Hesheng, Xuan, Yongli, Wang, Ye, Xue, Mei, Suo, Fei, Li, Xiaolu, Cheng, Wenjuan, Li, Xinran, Yin, Jie, Liu, Ju, Yan, Suhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995702/
https://www.ncbi.nlm.nih.gov/pubmed/24755692
http://dx.doi.org/10.1371/journal.pone.0095106