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Separate and Combined Effects of DNMT and HDAC Inhibitors in Treating Human Multi-Drug Resistant Osteosarcoma HosDXR150 Cell Line

Understanding the molecular mechanisms underlying multi-drug resistance (MDR) is one of the major challenges in current cancer research. A phenomenon which is common to both intrinsic and acquired resistance, is the aberrant alteration of gene expression in drug-resistant cancers. Although such dysr...

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Detalles Bibliográficos
Autores principales: Capobianco, Enrico, Mora, Antonio, La Sala, Dario, Roberti, Annalisa, Zaki, Nazar, Badidi, Elarbi, Taranta, Monia, Cinti, Caterina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995708/
https://www.ncbi.nlm.nih.gov/pubmed/24756038
http://dx.doi.org/10.1371/journal.pone.0095596