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Lymphocytes from chronic lymphocytic leukaemia undergo ABL1-linked amoeboid motility and homotypic interaction as an early adaptive change to ex vivo culture

BACKGROUND: Those stimuli that together promote the survival, differentiation and proliferation of the abnormal B-lymphocytes of chronic lymphocytic leukaemia (CLL) are encountered within tissues, where together they form the growth-supporting microenvironment. Different tissue-culture systems promo...

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Detalles Bibliográficos
Autores principales: Hutchinson, Claire V, Natarajan, Shiva, Johnson, Suzanne M, Adams, Julie A, Rees-Unwin, Karen S, Burthem, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995717/
https://www.ncbi.nlm.nih.gov/pubmed/24618035
http://dx.doi.org/10.1186/2162-3619-3-7