PTEN: A master regulator of neuronal structure, function, and plasticity

PTEN (phosphatase and tensin homolog on chromosome ten) is a dual protein/lipid phosphatase that dephosphorylates PIP3, thereby inhibiting the AKT/mTOR pathway. This inhibition ultimately decreases protein translation, cell proliferation and cell growth. In the central nervous system, inhibition of...

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Detalles Bibliográficos
Autores principales: Garcia-Junco-Clemente, Pablo, Golshani, Peyman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995733/
https://www.ncbi.nlm.nih.gov/pubmed/24778766
http://dx.doi.org/10.4161/cib.28358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995733/
https://www.ncbi.nlm.nih.gov/pubmed/24778766
http://dx.doi.org/10.4161/cib.28358

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