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PTEN: A master regulator of neuronal structure, function, and plasticity

PTEN (phosphatase and tensin homolog on chromosome ten) is a dual protein/lipid phosphatase that dephosphorylates PIP3, thereby inhibiting the AKT/mTOR pathway. This inhibition ultimately decreases protein translation, cell proliferation and cell growth. In the central nervous system, inhibition of...

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Detalles Bibliográficos
Autores principales:	Garcia-Junco-Clemente, Pablo, Golshani, Peyman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2014
Materias:	Mini Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995733/ https://www.ncbi.nlm.nih.gov/pubmed/24778766 http://dx.doi.org/10.4161/cib.28358

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