The involvement of JAK-STAT3 in cell motility, invasion, and metastasis

JAK-STAT3 signaling, while regulating many aspects of cancer development and progression, promotes invasion and metastasis through activation of key metastasis promoting genes such as WASF3. STAT3 promotes WASF3 expression and JAK2 independently activates it, which is required for invasion. JAK-STAT...

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Detalles Bibliográficos
Autores principales: Teng, Yong, Ross, James L, Cowell, John K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2014
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995737/
https://www.ncbi.nlm.nih.gov/pubmed/24778926
http://dx.doi.org/10.4161/jkst.28086

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995737/
https://www.ncbi.nlm.nih.gov/pubmed/24778926
http://dx.doi.org/10.4161/jkst.28086

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