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Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling

BACKGROUND: Paroxetine, a selective serotonin reuptake inhibitor for counteracting depression, has been recently suggested as having a role in prevention of dopaminergic neuronal degeneration in substantia nigra, a hallmark of Parkinson’s disease (PD). The pathogenesis of this type of neurological d...

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Detalles Bibliográficos
Autores principales: Liu, Rong-Pei, Zou, Ming, Wang, Jian-Yong, Zhu, Juan-Juan, Lai, Jun-Mei, Zhou, Li-Li, Chen, Song-Fang, Zhang, Xiong, Zhu, Jian-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995780/
https://www.ncbi.nlm.nih.gov/pubmed/24618100
http://dx.doi.org/10.1186/1742-2094-11-47