Cargando…

Paroxetine ameliorates lipopolysaccharide-induced microglia activation via differential regulation of MAPK signaling

BACKGROUND: Paroxetine, a selective serotonin reuptake inhibitor for counteracting depression, has been recently suggested as having a role in prevention of dopaminergic neuronal degeneration in substantia nigra, a hallmark of Parkinson’s disease (PD). The pathogenesis of this type of neurological d...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Rong-Pei, Zou, Ming, Wang, Jian-Yong, Zhu, Juan-Juan, Lai, Jun-Mei, Zhou, Li-Li, Chen, Song-Fang, Zhang, Xiong, Zhu, Jian-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995780/ https://www.ncbi.nlm.nih.gov/pubmed/24618100 http://dx.doi.org/10.1186/1742-2094-11-47

Ejemplares similares

Paroxetine suppresses reactive microglia-mediated but not lipopolysaccharide-induced inflammatory responses in primary astrocytes
por: Zhang, Xiong, et al.
Publicado: (2020)

Redox-sensitive MAPK and Notch3 regulate fibroblast differentiation and activation: a dual role of ERK1/2
por: Lai, Jun-Mei, et al.
Publicado: (2016)

Oxycodone ameliorates the inflammatory response induced by lipopolysaccharide in primary microglia
por: Ye, Jishi, et al.
Publicado: (2018)

Paroxetine overdose
por: Gupta, Arun K., et al.
Publicado: (2005)

Paroxetine ameliorates prodromal emotional dysfunction and late-onset memory deficit in Alzheimer’s disease mice
por: Ai, Peng-Hui, et al.
Publicado: (2020)

Antidepressant and Neuroprotective Effects of 3-Hydroxy Paroxetine, an Analog of Paroxetine in Rats
por: Hernández-Arrambide, Pedro Efraín, et al.
Publicado: (2022)

Paroxetine combined with olanzapine in the treatment of schizophrenia
por: Wang, Ning, et al.
Publicado: (2020)

Ubiquitin-specific protease 8 ameliorates lipopolysaccharide-induced spleen injury via suppression of NF-κB and MAPK signaling pathways
por: Bi, Wei, et al.
Publicado: (2022)

Targeting MAPK Pathways by Naringenin Modulates Microglia M1/M2 Polarization in Lipopolysaccharide-Stimulated Cultures
por: Zhang, Bei, et al.
Publicado: (2019)

Paroxetine-induced galactorrhea
por: Gulati, Prannay, et al.
Publicado: (2014)

Paroxetine-induced galactorrhea
por: Petrykiv, S., et al.
Publicado: (2022)

Pharmacokinetics of immediate and sustained-release formulations of paroxetine: Population pharmacokinetic approach to guide paroxetine personalized therapy in chinese psychotic patients
por: Li, Xiao-lin, et al.
Publicado: (2022)

Comparison Between Tadalafil Plus Paroxetine and Paroxetine Alone in the Treatment of Premature Ejaculation
por: Moudi, Emadouddin, et al.
Publicado: (2016)

Paroxetine ameliorates changes in hippocampal energy metabolism in chronic mild stress-exposed rats
por: Khedr, Lobna H, et al.
Publicado: (2015)

Fucoxanthinol from the Diatom Nitzschia Laevis Ameliorates Neuroinflammatory Responses in Lipopolysaccharide-Stimulated BV-2 Microglia
por: Li, Yuelian, et al.
Publicado: (2020)

Effectiveness of paroxetine in the treatment of poststroke depression
por: Ma, Chen, et al.
Publicado: (2018)

Paroxetine‐induced QTc prolongation
por: Otsuka, Yuji
Publicado: (2017)

Paroxetine overdose during pregnancy
por: Acar, Selin, et al.
Publicado: (2021)

Magnoflorine Ameliorates Lipopolysaccharide-Induced Acute Lung Injury via Suppressing NF-κB and MAPK Activation
por: Guo, Shuai, et al.
Publicado: (2018)

Inclusion Scenarios and Conformational Flexibility of the SSRI Paroxetine as Perceived from Polymorphism of β-Cyclodextrin–Paroxetine Complex
por: Aree, Thammarat
Publicado: (2022)

Blockage of Autophagic Flux and Induction of Mitochondria Fragmentation by Paroxetine Hydrochloride in Lung Cancer Cells Promotes Apoptosis via the ROS-MAPK Pathway
por: Wang, Kun, et al.
Publicado: (2020)

Hsp22 ameliorates lipopolysaccharide-induced myocardial injury by inhibiting inflammation, oxidative stress, and apoptosis
por: Yu, Yun, et al.
Publicado: (2021)

Puerarin Ameliorates Caerulein-Induced Chronic Pancreatitis via Inhibition of MAPK Signaling Pathway
por: Zeng, Xiang-Peng, et al.
Publicado: (2021)

Paroxetine—Overview of the Molecular Mechanisms of Action
por: Kowalska, Magdalena, et al.
Publicado: (2021)

Artemisinin Attenuates Lipopolysaccharide-Stimulated Proinflammatory Responses by Inhibiting NF-κB Pathway in Microglia Cells
por: Zhu, Cansheng, et al.
Publicado: (2012)

Agomelatine versus paroxetine in treating depressive and anxiety symptoms in patients with chronic kidney disease
por: Chen, Jian-wei, et al.
Publicado: (2018)

Efficacy of cognitive behavioral therapy with paroxetine and paroxetine only for social anxiety disorder: A behavioral, placebo-controlled study
por: Samantray, Narendranath, et al.
Publicado: (2019)

Differential expression of E-type prostanoid receptors 2 and 4 in microglia stimulated with lipopolysaccharide
por: Bonfill-Teixidor, Ester, et al.
Publicado: (2017)

Paroxetine alleviates T lymphocyte activation and infiltration to joints of collagen-induced arthritis
por: Wang, Qingtong, et al.
Publicado: (2017)

Hemokinin-1 Gene Expression Is Upregulated in Microglia Activated by Lipopolysaccharide through NF-κB and p38 MAPK Signaling Pathways
por: Sakai, Atsushi, et al.
Publicado: (2012)

Combination of valproate and paroxetine in mice exposed to picrotoxin
por: Kamal, Sahar M
Publicado: (2012)

Paroxetine in the treatment of recurrent brief depressive disorder
por: Prakash, Sathya, et al.
Publicado: (2013)

Mirtazapine in Paroxetine Induced Hyper-prolactinemic Galactorrhoea
por: Singh, Manjeet, et al.
Publicado: (2015)

Mechanism of Paroxetine (Paxil) Inhibition of the Serotonin Transporter
por: Davis, Bruce A., et al.
Publicado: (2016)

Critical appraisal of paroxetine for the treatment of vasomotor symptoms
por: Carroll, Dana G, et al.
Publicado: (2015)

Extra-Paramidal Side Effects Associated with Paroxetine
por: Nicholson, Simon D.
Publicado: (1992)

Successful Use of Risperidone, Trihexyphenidyl, and Paroxetine in Pregnancy
por: Goyal, Sandeep Kumar, et al.
Publicado: (2017)

Euprolactinemic Galactorrhea with Paroxetine: Exploring the Missing Link
por: Mishra, Shree, et al.
Publicado: (2019)

Musical Hallucinations Induced by Conventional Doses of Paroxetine
por: Muraosa, Haruka, et al.
Publicado: (2020)

The Antidepressant Paroxetine Reduces the Cardiac Sodium Current
por: Plijter, Ingmar S., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_1cjnhnphtg29o79h5ciopf1u6d