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Long-term exposure to muscarinic agonists decreases expression of contractile proteins and responsiveness of rabbit tracheal smooth muscle cells

BACKGROUND: Chronic airway diseases, like asthma or COPD, are characterized by excessive acetylcholine release and airway remodeling. The aim of this study was to investigate the long-term effect of muscarinic agonists on the phenotype and proliferation of rabbit tracheal airway smooth muscle cells...

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Detalles Bibliográficos
Autores principales: Stamatiou, Rodopi, Paraskeva, Efrosini, Vasilaki, Anna, Mylonis, Ilias, Molyvdas, Paschalis Adam, Gourgoulianis, Konstantinos, Hatziefthimiou, Apostolia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995846/
https://www.ncbi.nlm.nih.gov/pubmed/24607024
http://dx.doi.org/10.1186/1471-2466-14-39